Hypothermia for newborns with hypoxic ischemic encephalopathy

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Hypothermia for newborns with hypoxic ischemic encephalopathy.

Hypoxic ischemic encephalopathy (HIE) remains a significant cause of mortality and long-term disability in late preterm and term infants. Mild therapeutic hypothermia to a rectal temperature of 34±0.5°C initiated as soon as possible within the first 6 h of life decreases mortality and severe long-term neurodevelopmental disabilities in infants with moderate HIE who are ≥36 weeks' gestational ag...

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Hypothermia therapy for newborns with hypoxic ischemic encephalopathy.

OBJECTIVE Therapeutic hypothermia reduces cerebral injury and improves the neurological outcome secondary to hypoxic ischemic encephalopathy in newborns. It has been indicated for asphyxiated full-term or near-term newborn infants with clinical signs of hypoxic-ischemic encephalopathy (HIE). SOURCES A search was performed for articles on therapeutic hypothermia in newborns with perinatal asph...

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[Meta-analysis of mild hypothermia for gestational age over 35-week newborns with hypoxic-ischemic encephalopathy].

OBJECTIVE To determine the effects of therapeutic hypothermia (TH) in encephalopathic asphyxiated newborn infants on mortality, long-term neurodevelopmental disability and side effects by summarizing the data of hypoxic-ischemic encephalopathy(HIE) newborns undergoing mild hypothermia using meta-analysis. METHODS The standard searching strategy of the Neonatal Review Group as outlined in the ...

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Value of electroencephalographic monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia

BACKGROUND The values of electroencephalography (EEG) in neonatal hypoxic-ischemic encephalopathy (HIE) during therapeutic hypothermia (TH) are still uncertain. AIMS The aim of this study is to detect EEG background, the prevalence of seizures during cooling, and to determine different EEG patterns that can predict brain injury in magnetic resonance imaging (MRI). PATIENTS AND METHODS Thirt...

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Impaired cerebral autoregulation and brain injury in newborns with hypoxic-ischemic encephalopathy treated with hypothermia.

Impaired cerebral autoregulation may contribute to secondary injury in newborns with hypoxic-ischemic encephalopathy (HIE). Continuous, noninvasive assessment of cerebral pressure autoregulation can be achieved with bedside near-infrared spectroscopy (NIRS) and systemic mean arterial blood pressure (MAP) monitoring. This study aimed to evaluate whether impaired cerebral autoregulation measured ...

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ژورنال

عنوان ژورنال: Paediatrics & Child Health

سال: 2012

ISSN: 1205-7088,1918-1485

DOI: 10.1093/pch/17.1.41